Multiple Sclerosis Iron MRI Linked to Cognitive Impairment in 12 Studies
A 2026 systematic review of advanced neuroimaging in multiple sclerosis narrowed 600 database records to 12 studies and found the clearest cognition signal in basal ganglia iron-sensitive MRI measures, while thalamic susceptibility was more variable and often tangled with atrophy. Research Highlights Basal ganglia signal was strongest: across 12 studies, elevated susceptibility or iron-related metrics …