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Migraine Linked to Cognitive Impairment in Chinese MR

Editorial card showing a brain with migraine pain pathways overlaid on genetic instrument schematic for Mendelian randomization.

A 2026 study by Bai et al. in Dialogues in Clinical Neuroscience uses Mendelian randomization (MR) — inherited genetic variants as a natural experiment to test causality — and concludes that migraines causally lower cognitive performance in a Han Chinese sample.1 The headline conclusion is plausible; the effect-size numbers in the popular MR shorthand (odds …

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