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Vraylar (Cariprazine) Withdrawal Symptoms: What To Expect After Discontinuation

Vraylar (Cariprazine) is an atypical antipsychotic that is most frequently prescribed as a pharmacological intervention for schizophrenia and bipolar disorder.  The medication functions predominantly as a: D3 and D2 receptor partial agonist, 5-HT2B receptor antagonist, and 5-HT1A partial agonist.  To a less significant extent, Vraylar interacts with H1 receptors and 5-HT2A receptors as an antagonist.  …

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Vraylar (Cariprazine) Side Effects & Adverse Reactions

Vraylar (Cariprazine), is an atypical antipsychotic medication approved in 2015 by the FDA for the treatment of schizophrenia and bipolar disorder.  Occasionally, Vraylar is also prescribed as an adjunct for treatment-resistant depression and off-label for anxiety disorders.  Although Vraylar is marketed as an improvement over older atypical antipsychotic medications in terms of efficacy and tolerability, …

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Vraylar (Cariprazine) & Weight Gain vs. Loss: What You Should Know

Vraylar (Cariprazine), also sold under the name Reagila [in European countries], is an atypical antipsychotic developed by the pharmaceutical company Allergan.  In 2015, Vraylar received FDA approval for the treatment of schizophrenia and mania associated with bipolar disorder.  From a pharmacodynamic perspective, Vraylar functions predominantly as a partial agonist at D3 and D2 dopamine receptors, …

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Vraylar (Cariprazine) Approved For Schizophrenia & Bipolar Disorder

Vraylar (Cariprazine) was approved by the FDA on September 17, 2015 for the treatment of schizophrenia and mania associated with bipolar disorder.  In clinical trials, the drug was referenced as “RGH-188” – containing Cariprazine as the primary active ingredient.  The drug had completed Phase III clinical trials in 2012, and was pending FDA approval for …

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3 New Bipolar Medications (2015): Drugs In Clinical Trials

Bipolar disorder is a condition characterized by cyclical mood swings, transitioning from depression to mania (or hypomania).  For a period of time, an individual with bipolar disorder will experience debilitating bouts of depression – and often unexpectedly, their entire neurophysiology will shift to facilitate a state of mania (elevated mood).  Diagnostically, there are multiple types …

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