Cannabis Abstinence: Frequent Use Did Not Increase Acute Pain in 75 Adults
A 2026 laboratory study found no detectable acute-pain increase in frequent cannabis users after at least 12 hours of biochemically verified abstinence. Frequent users had higher THC exposure and higher plasma cannabinoid markers, but pain threshold, pain tolerance, and pain ratings did not differ from occasional users.1 Research Highlights 75 healthy adults were tested: Pabon …