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Right OFC rTMS Improves Memory in Early Schizophrenia

Editorial card showing a coronal brain section highlighting the right orbitofrontal cortex with a TMS coil, illustrating the first RCT of OFC stimulation in first-episode schizophrenia.

Cognitive impairment in first-episode schizophrenia (FES) is the symptom that does the most work blocking employment, relationships, and independent living — and the symptom current antipsychotics barely move. A 2026 RCT by Hu et al. in Psychological Medicine tested whether 20 sessions of low-frequency rTMS targeting the right orbitofrontal cortex (OFC) could improve cognition where …

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