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Under-Mattress Sensors Predict Dementia Agitation: 333-Night Cohort

Stylized illustration of an under-mattress sensor connected to a clock and waveform pattern, indicating overnight respiratory and movement signals predicting next-day behavioral risk in a dementia care setting.

Daytime agitation in dementia fluctuates day-to-day, and a 2026 explanatory study from Liu et al. used contactless under-mattress sensors in 55 long-term-care residents and an external 17-person home-monitoring cohort to show that lower nocturnal respiratory rate and higher activity instability robustly predict next-day agitation occurrence — but not severity.1 Research Highlights Lower breathing rate: adjusted …

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Risperidone in Dementia Raised Stroke-Related Events 4.11x by Week 4

MHD featured image for risperidone adverse events in dementia.

A 2026 individual participant data meta-analysis of 1,721 dementia trial participants linked risperidone to cerebrovascular adverse events, HR 4.11 (95% CI 1.77 to 9.51), and major cardiovascular adverse events, HR 2.00 (95% CI 1.23 to 3.26).1 The timing signal is the practical warning: median first cerebrovascular event appeared at 4.3 weeks, and median first major …

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