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Brazilian Eating Disorder Guidelines: CBT First for Bulimia and Binge Eating, Fewer Proven Options for Anorexia

MHD card with an open glowing guideline book on a dark navy background, three colored pathways branching from its spine to three nodes, and stepped translucent evidence tiers at the right edge, illustrating eating disorder treatment guidelines.

New Brazilian Psychiatric Association guidelines put cognitive behavioral therapy (CBT) first for bulimia and binge-eating disorder. When medication is needed, they recommend fluoxetine as an add-on for bulimia and lisdexamfetamine as the first-choice drug for binge-eating disorder. For anorexia, no single therapy has proven best, and drugs play only a small supporting role.1 Research Highlights …

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Naltrexone/Bupropion Reduced Food Intake in Binge-Eating Lab Study

Photoreal illustration of brain reward circuitry overlaid on imagery of palatable food, conveying pharmacological reduction of consummatory reward.

Lisdexamfetamine remains the only FDA-approved medication for binge-eating disorder — a serious condition affecting roughly 1.2% of adults. A 2026 human laboratory study by McKee and colleagues tests whether naltrexone/bupropion, already approved for obesity, reduces the food-reward mechanisms that drive binge episodes.1 Research Highlights Binge-eating disorder (BED) is the most common eating disorder in the …

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