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150 mg Caffeine Did Not Trigger Panic in Panic Disorder Trial

MHD featured image for caffeine and panic disorder challenge research.

A randomized crossover trial found that 150 mg caffeine did not increase subjective anxiety, interoceptive attention, or anxiety from body sensations in 29 people with panic disorder compared with 53 healthy controls.1 The result runs opposite the hypothesis, but it does not make caffeine inert: caffeine still increased physiological arousal, costly avoidance, and attention problems …

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