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Lithium Loading Dose Did Not Clearly Beat Standard Acute-Mania Titration

Photoreal illustration of lithium tablets and blood-level monitoring chart, conveying acute-mania pharmacological strategy.

A 60-patient randomized trial of lithium loading for acute bipolar I mania reported faster serum lithium attainment than standard titration and a larger 14-day Young Mania Rating Scale (YMRS) change score, but the same accepted manuscript says absolute YMRS scores at Days 3, 7, and 14 were not significantly different between the 2 arms when …

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Rexulti (Brexpiprazole) Approved For Schizophrenia & Depression (Adjunct)

Rexulti (Brexpiprazole) is a drug that was approved July 10, 2015 for the treatment of schizophrenia and as an adjunctive option for major depressive disorder.  In clinical trials it was referred to as the chemical “OPC-34712” and is being marketed as a superior successor to Abilify (Aripiprazole) due to the fact that Abilify’s patent expired …

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Robin Williams Suicide Causes: Dementia or Antidepressants To Blame?

Most people are aware of the recent tragedy involving well-known actor and comedic legend Robin Williams. Although he was an extremely talented actor with a brilliant comedic talent, he commit suicide on August 11, 2014. This sent most of his close family members, friends, celebrities, and even the general public into shock. Most people were …

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