systemic inflammation Archives

Heart Failure Depression Linked to Oral Health and Microbiome Dysbiosis

by GLOOM

MHD featured image for emotional disorders, heart failure, and oral microbiome research.

A 2026 analysis linked emotional disorders in heart failure to poorer cardiovascular health, oral-health burden, and oral microbiome dysbiosis, but the strongest mediation signal came from oral health rather than systemic immune-inflammation index.1 In fully adjusted NHANES models, emotional disorders were associated with lower Life’s Essential 8 cardiovascular health, OR 0.39, while self-rated oral health …

Sleep Disorders vs. Systemic Immune-Inflammation Index (SII) in the U.S. Population (2023 Study)

by GLOOM

Sleep and inflammation have long been topics of scientific inquiry, with a growing body of evidence underscoring their intricate relationship. The systemic immune-inflammation index (SII), a novel marker based on leukocyte parameters, has emerged as a significant indicator of systemic inflammation. A recent study explored the association between sleep-related disorders and SII, revealing intriguing connections …