Subthreshold Depression Linked to Inflammation and Altered Brain Connectivity
University students with subthreshold depression, meaning real depressive symptoms that fall short of a major depression diagnosis, had stronger connections in 3 cingulate brain circuits and slightly higher levels of 3 inflammatory proteins than healthy students, according to a 2026 brain-imaging study from China.1 Research Highlights Stronger cingulate connections: resting brain scans of 126 students …