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Gene Editing with CRISPR/Cas9 to Treat Corticosteroid-Induced Neuropsychiatric Disorders (2023 Review)

The widespread use of corticosteroids (CCSs) across the globe for treating inflammatory conditions has led to an increased incidence of corticosteroid-induced neuropsychiatric disorders (NPDs), raising significant public health concerns. These disorders range from depression and anxiety to severe cognitive changes, challenging the medical community to find effective treatments. The exploration of genetic and epigenetic factors …

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Anabolic Androgenic Steroids vs. Sleep Quality & Psychological Distress in Weightlifters (2024 Study)

Recent research has analyzed the relationship between the use of Anabolic Androgenic Steroids (AAS), sleep quality, and psychological distress. A new study specifically evaluated the effects of anabolic steroids on sleep patterns during both active use and withdrawal phases, among male weightlifters in Norway. Highlights: A large proportion of men using AAS report experiencing sleep …

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Why Prednisone Causes Weight Gain (And What To Do About It)

Prednisone is a synthetic pregnane corticosteroid that was first identified in 1950 by the American microbiologist Arthur Nobile, and thereafter, synthesized in 1955 by the Schering Corporation.  As a synthetic derivative of cortisone, prednisone acts by mimicking the physiologic effects of cortisol, the chief endogenous hormone secreted by the adrenal cortex when the body is …

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Post Acute Withdrawal Syndrome: Causes, Symptoms, Treatment

Individuals that have used any potent drug, particularly for a long-term and/or at high doses are known to experience significant short-term withdrawal symptoms.  These symptoms may include things like dizziness, headaches, nausea, and vomiting.  Over time, they usually lessen in severity as the nervous system and physiology adjusts to function without the presence of the …

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