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Losartan, Especially as Nanoparticles, Eased Cerebellum Damage in Rats

MHD card showing a glowing emerald cerebellum with a tree-like inner branching pattern dotted with amber nanoparticle spheres and a faint rat silhouette, illustrating a rat study in which losartan eased toxin damage to the cerebellum.

In rats with toxin-damaged cerebellums, 4 weeks of the blood-pressure drug losartan reduced oxidative damage, inflammation and tissue injury. A nanoparticle version did better on several tissue and staining measures, but not on gene activity.1 Research Highlights A small rat experiment: 24 male rats in 4 groups of 6. Three groups received carbon tetrachloride (a …

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