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Blood microRNAs Linked to Hippocampal Atrophy in Rhineland Study

MHD featured image for blood microRNA signatures and hippocampal atrophy.

A 2026 Molecular Psychiatry analysis from the Rhineland Study found that blood-derived microRNA signatures were associated with hippocampal brain structure: 6 microRNAs linked cross-sectionally to left hippocampal volume, and 5 different microRNAs linked longitudinally to hippocampal atrophy rates.1 The result is biomarker-discovery evidence for brain aging, not a ready dementia blood test. Research Highlights Baseline …

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