qMRI Brain Aging Maps Myelin, Iron, and Water in 138 Adults
A 2026 quantitative MRI preprint reanalyzed 138 healthy adults and found that multivariate modeling detected coordinated age-related shifts across myelin-sensitive, iron-sensitive, and water-sensitive brain maps.1 The signal was broad, but split-half validation weakened the result enough to keep it in the measurement-method lane rather than the clinical-test lane. Research Highlights 138 adults were reanalyzed: The …