PPMI

Published research on PPMI.

DepressionJul 16, 2026

Lower Uric Acid Predicted Depression in Prodromal Parkinson’s Disease

A 5-year PPMI cohort analysis found that lower serum uric acid independently predicted incident depression in prodromal Parkinson’s disease (HR = 0.776; 95% CI 0.619-0.974; P = 0.029).1 The …

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DrugsMay 20, 2026

Alpha-Synuclein SAA Predicts Parkinson’s Levodopa Response Durability

A 2026 PPMI analysis found that Parkinson’s patients with positive CSF α-synuclein seed amplification assay results kept gaining levodopa benefit over follow-up, while SAA-negative patients …

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