MentalHealthDaily

Dynamic FDG-PET Signal Quality Beats Static PET in Focal Epilepsy

by GLOOM

MHD featured image for dynamic FDG-PET signal quality in focal epilepsy neuroimaging.

A 2026 medRxiv study of 30 adults with drug-resistant focal epilepsy found that dynamic FDG-PET had higher model-adjusted signal quality than static PET in most brain regions, including >80% posterior probability of superiority in 29 of 36 regions. Research Highlights Dynamic PET beat static PET: interictal dynamic FDG-PET showed higher signal quality than static PET …

Post-Stroke Depression Tracks Serotonin-Acetylcholine Damage

by GLOOM

Photoreal illustration of stroke lesion with overlapping neurotransmitter network damage, conveying mechanism of post-stroke depression.

A 2026 two-cohort connectome study found that post-stroke depressive symptoms tracked damage to networks weighted by the serotonin transporter and vesicular acetylcholine transporter: 5-HTT damage predicted depression in Leipzig (OR 2.4, 95% CI 1.15–5.02) and Oxford (OR 2.05, 95% CI 1.03–4.09), while VAChT damage also replicated across both cohorts.1 The dopamine part of the original …