inborn errors of immunity Archives

Primary Immunodeficiency: Self-Isolation Linked to Depression and Anxiety

by GLOOM

MHD card showing a lone figure under a glass dome behind a lit window, with a face mask on the sill and faint immune-cell shapes outside, illustrating a study in which self-isolation was linked to depression and anxiety in adults with immune disorders.

Adults with inborn errors of immunity, also called primary immunodeficiency, who cut back social contact to avoid infections reported more depression and anxiety symptoms. A 2026 German clinic study of 143 patients also found that about 1 in 4 people with significant symptoms had never been diagnosed.1 Research Highlights Isolation went with higher symptom scores: …