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Treatment-Resistant Schizophrenia Affects 28.6% of Assessed Inpatients in Japan

MHD card with a 10-person pictogram in 2 rows on a dark amber background, 3 figures lit in orange, beside a key whose bow is a 2-tone capsule, illustrating that nearly 3 in 10 assessed inpatients in Japan had treatment-resistant schizophrenia.

A 2026 nationwide study in Japan found that 28.6% of hospitalized patients with schizophrenia who were checked for treatment resistance met the criteria.1 Nearly half of those patients left the hospital on clozapine, the only antipsychotic with established benefit for this form of the illness. Research Highlights Large real-world sample: records covered 18,914 inpatients discharged …

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