Targeting the Nucleus Accumbens D1-MSN cAMP for Depression & Crocin’s Rapid Antidepressant Effect (2024 Study)
Depression, a debilitating mental health disorder, has long puzzled scientists and clinicians alike. Recent research sheds light on the nucleus accumbens (NAc), a brain region associated with reward and pleasure, highlighting its critical role in the pathophysiology of depression. Specifically, the study shows how manipulating cyclic adenosine monophosphate (cAMP) levels within dopamine D1 receptor medium …