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Multiple Sclerosis Personalized Therapy: 70% Delphi Consensus

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An Italian multiple sclerosis Delphi panel reached consensus on 116 of 166 votes, meaning 70% of expert votes aligned and 30% still exposed disagreement about personalized therapy, patient involvement, and treatment sequencing.1 The result supports individualized MS treatment planning, but it is consensus evidence rather than proof that one disease-modifying therapy fits every high-risk patient. …

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Multiple Sclerosis B-Cell Repertoires Shift After DMD Treatment

MHD featured image for multiple sclerosis, B-cell repertoires, and disease-modifying therapy effects.

A 2026 Journal of Neuroinflammation study involving 33 people with multiple sclerosis and 10 healthy controls found disease-specific B-cell repertoire signatures even when ordinary B-cell subset counts looked modest, then showed that most disease-modifying therapies shifted repertoire diversity after 6 months. Research Highlights Repertoire sequencing found MS signal: Vasilenko et al. analyzed more than 196,100,000 …

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