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Morganella Phospholipids Triggered IL-6 in Depression Mechanism Study

MHD featured image for Morganella gut bacteria, phospholipids, and depression-related inflammation.

A 2025 Journal of the American Chemical Society study identified 4 unusual Morganella morganii phospholipids that activated TLR2/TLR1 immune receptors and induced inflammatory cytokines, especially IL-6.1 The finding does not prove that one gut bacterium causes depression, but it gives the microbiome-depression field something it often lacks: a named molecule and a receptor pathway. Research …

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