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Ketamine Increases Amygdala Volume in Treatment-Resistant Depression (TRD) (2024 MRI Study)

Depression is a complex mental health condition that significantly affects an individual’s emotional and physical well-being. Recent advances in neuroimaging have provided deeper insights into how major depressive disorder (MDD) alters brain structures, particularly the hippocampus and amygdala, and how treatments like ketamine can potentially reverse these changes. A new study using 3T and 7T …

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Effects of Coffee & Caffeine on Brain Connectivity in Habitual Drinkers (2023 Study)

Coffee, one of the world’s most consumed beverages, is often lauded for its ability to enhance alertness and cognitive performance. Recent studies utilizing advanced neuroimaging techniques like resting-state functional magnetic resonance imaging (fMRI) have begun to unravel the intricate ways in which coffee, and its key component caffeine, modulate brain activity. This exploration into the …

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Cannabidiol (CBD): Neuropsychiatric Uses, Mechanisms, Effects on Brain (2023 Review)

Cannabidiol (CBD), a compound found in Cannabis sativa, has emerged as a substance of interest in the medical community due to its potential therapeutic benefits for various neurological and mental disorders. This comprehensive review examines the current scientific understanding of CBD’s effects on brain function, its potential as a therapeutic agent, and the ethical and …

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Neuromodulation Therapies to Treat Neuroinflammation in Anxiety & Depression (2023 Research)

The intersection of neuromodulation, neuroinflammation, and their roles in mood disorders like anxiety and depression represents a significant stride in mental health research. This complex interplay underscores the potential of novel therapeutic strategies targeting the brain’s inflammatory pathways, offering new hope for effective management of these pervasive conditions. Highlights: Link Between Neuroinflammation and Mood Disorders: …

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Lateral Habenula & Depression: The Anti-Reward Center (Mechanisms & Antidepressant Treatments)

Depression is a complex and multifaceted disorder affecting millions worldwide. Emerging evidence suggests the lateral habenula, a small brain region, plays a crucial role in depression’s development and persistence. By influencing neurotransmitter systems and interacting with stress pathways, the lateral habenula’s dysfunction may lead to the classic symptoms of depression. Highlights: The lateral habenula is …

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