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77-Drug Blood Screen Found Benzodiazepines in 37.9% of Detections

MHD featured image for neuropsychiatric drug blood screening and benzodiazepine detections.

A 2026 clinical-lab study tested a 77-drug liquid chromatography-tandem mass spectrometry serum screen in 1,021 patients and found that benzodiazepines accounted for 37.9% of all detections, ahead of antidepressants and antipsychotics.1 Emergency-department cases were a small slice of the sample, but they were positive more often than outpatients: 85.2% vs. 59.5%. Research Highlights Benzodiazepines dominated …

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