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Drugs

Zuranolone for Depression: Rapid Efficacy & Safety in Clinical Trials (2023 Review)

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Zuranolone, a novel antidepressant, shows promise in treating depression, as evidenced by a recent meta-analysis. A new study investigated zuranolone’s efficacy and safety, focusing on short-term rapid antidepressant effects. Highlights: Zuranolone Effectiveness: Demonstrated significant improvement in depression severity scores compared to placebo, with notable effects by day 15. Treatment-Emergent Adverse Events (TEAEs): Increased incidence in …

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Black Cumin (Nigella Sativa) Seed Oil Extract (BCO-5) May Improve Non-Restorative Sleep (2023 Study)

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Sleep is a fundamental aspect of human health, deeply intertwined with our overall well-being. Recent research examined a unique black cumin extract, BCO-5, and found that it may be beneficial in individuals with non-restorative sleep disorders. Highlights: BCO-5, a Unique Black Cumin Extract: BCO-5 is a proprietary extract of Nigella sativa (black cumin) showing promising …

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Latest Treatments for Frontotemporal Dementia (FTD): High-Dose Oxytocin Emerges as the Standout (2023 Review)

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Frontotemporal dementia (FTD) is a challenging and impactful neurodegenerative disease. Recent research offers new insights into its management, particularly regarding the effectiveness of pharmacological treatments. Highlights: High-Dose Oxytocin Shows Promise: High-dose oxytocin (72 international units) has been linked to significant improvements in neuropsychiatric symptoms and daily interactive activities in FTD patients. Piracetam Poses Risks: Contrarily, …

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SSRI-Induced Sexual Dysfunction Reversed with “Drug Holidays” on Weekends (2024 Study)

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Selective serotonin reuptake inhibitors (SSRIs) are a mainstay in the treatment of various mental disorders but often come with the unwelcome side effect of sexual dysfunction. This issue can significantly affect patients’ adherence to their medication regime, often leading to treatment discontinuation. A recent clinical trial offers a new perspective, suggesting that ‘drug holidays’ – …

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Cannabis (Marijuana) Use & Psychosis: Does It Increase Risk? (2023 Evidence Review)

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The relationship between cannabis (marijuana) use and psychosis has been a topic of considerable scientific interest and public health concern. With changing legal statuses and societal attitudes towards cannabis use in many countries, understanding this relationship is more critical than ever. Highlights: Systematic reviews and meta-analyses show a consistent association between cannabis use and increased …

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Reset Modafinil Tolerance with Drug Holidays & Pitolisant-Bridging? (2023 Study)

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Narcolepsy, a chronic neurological disorder, significantly impacts the daily lives of those affected due to excessive daytime sleepiness (EDS). Modafinil has been a cornerstone in managing EDS, but its effectiveness can wane over time due to tolerance. An innovative approach, using the drug pitolisant during modafinil ‘drug holidays’, offers new hope for resetting tolerance and …

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Anabolic Androgenic Steroids vs. Sleep Quality & Psychological Distress in Weightlifters (2024 Study)

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Recent research has analyzed the relationship between the use of Anabolic Androgenic Steroids (AAS), sleep quality, and psychological distress. A new study specifically evaluated the effects of anabolic steroids on sleep patterns during both active use and withdrawal phases, among male weightlifters in Norway. Highlights: A large proportion of men using AAS report experiencing sleep …

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