Lower Uric Acid Predicted Depression in Prodromal Parkinson’s Disease
A 5-year PPMI cohort analysis found that lower serum uric acid independently predicted incident depression in prodromal Parkinson’s disease (HR = 0.776; 95% CI 0.619-0.974; P = 0.029).1 The signal sits beside a lower-p-value non-motor symptom predictor: higher MDS-UPDRS Part I scores also predicted depression (HR = 1.177; 95% CI 1.093-1.267; P < 0.001). Research ...