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Heart Failure Depression Linked to Oral Health and Microbiome Dysbiosis

MHD featured image for emotional disorders, heart failure, and oral microbiome research.

A 2026 analysis linked emotional disorders in heart failure to poorer cardiovascular health, oral-health burden, and oral microbiome dysbiosis, but the strongest mediation signal came from oral health rather than systemic immune-inflammation index.1 In fully adjusted NHANES models, emotional disorders were associated with lower Life’s Essential 8 cardiovascular health, OR 0.39, while self-rated oral health …

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