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Schizophrenia and Aging: Advanced, Not Accelerated

Two parallel timelines representing chronological vs. biological age in schizophrenia: an early offset at first episode, then parallel trajectories afterward — illustrating advanced rather than accelerated aging.

“Schizophrenia ages you faster” is the headline that gets repeated whenever a new biomarker study lands. The 2026 Fernandez-Egea, Garcia-Rizo and Kirkpatrick review — covering 170 studies across mortality, brain imaging, telomeres, epigenetic clocks, and metabolic markers — pushes back on that framing.2 The aging signal is genuine. “Accelerated” is the part that overshoots for …

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