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Toxoplasma gondii Infection in Schizophrenia Linked to High Glucocorticoid Levels in Hair (2024 Study)

The intricate dance between parasites, mental health, and stress hormones is a subject of growing scientific inquiry, offering fascinating insights into how microscopic organisms might influence human behavior and psychiatric conditions. A recent study delves into the relationship between Toxoplasma gondii (TG), a common protozoan parasite, and its potential impact on individuals with schizophrenia, focusing …

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Schizophrenia vs. Immune System Activation: Cellular Signatures & Genetic Analysis (2023 Study)

Schizophrenia (SCZ) is a complex psychiatric disorder that affects millions worldwide, with symptoms ranging from hallucinations to disorganized thinking. Research into the causative factors of SCZ has expanded into the realm of immunology, examining how immune system interactions with the brain might influence the development and progression of the disorder. A recent comprehensive study using …

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ADHD Genetics Linked to Autism & Schizophrenia But Not Other Psychiatric Conditions (2024 Study)

Attention Deficit Hyperactivity Disorder (ADHD) is a complex neurodevelopmental condition that significantly impacts individuals’ lives. Recent advancements in genetic research, particularly Mendelian Randomization (MR) studies, have begun to unravel the intricate genetic associations between ADHD and other psychiatric disorders, offering new insights into their comorbidities. By leveraging data from genome-wide association studies (GWAS), this research …

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Cannabis (Marijuana) Use & Psychosis: Does It Increase Risk? (2023 Evidence Review)

The relationship between cannabis (marijuana) use and psychosis has been a topic of considerable scientific interest and public health concern. With changing legal statuses and societal attitudes towards cannabis use in many countries, understanding this relationship is more critical than ever. Highlights: Systematic reviews and meta-analyses show a consistent association between cannabis use and increased …

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Genetic Risk for Low Vitamin D Linked to Lower Social Motivation in First-Episode Psychosis (2024 Study)

Recent research reveals a notable association between vitamin D levels and the severity of negative symptoms in individuals with first-episode psychosis (FEP). A new study explored the genetic predisposition towards lower vitamin D levels and its impact on symptom severity in schizophrenia and related disorders. Highlights: Vitamin D & Psychosis Connection: Lower levels of vitamin …

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MicroRNA Biomarkers May Help Diagnose Schizophrenia

Schizophrenia (SZ) is a complex psychiatric disorder characterized by a myriad of symptoms, typically divided into positive, negative, and cognitive categories. Despite the prevalence and severity of this condition, current diagnostic methods are largely based on subjective clinical interviews and observations, leading to potential misdiagnosis and delayed treatment. Recent studies have focused on microRNAs (miRNAs) …

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Vraylar (Cariprazine) & Weight Gain vs. Loss: What You Should Know

Vraylar (Cariprazine), also sold under the name Reagila [in European countries], is an atypical antipsychotic developed by the pharmaceutical company Allergan.  In 2015, Vraylar received FDA approval for the treatment of schizophrenia and mania associated with bipolar disorder.  From a pharmacodynamic perspective, Vraylar functions predominantly as a partial agonist at D3 and D2 dopamine receptors, …

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