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At-Home tDCS Trial (HomeDC) Prematurely Terminated Due to Skin Lesions & Safety Concerns (2023 Study)

Transcranial Direct Current Stimulation (tDCS) is emerging as a promising home-based treatment for Major Depressive Disorder (MDD), offering a non-invasive, cost-effective, and scalable option for patients. This treatment modulates cortical excitability, potentially altering neuronal activity in the brain areas associated with depression. However, a recent randomized controlled trial (RCT), the HomeDC trial, aimed at investigating …

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Personalized TMS for Psychiatric Disorders: Targeting Functional Connectivity (FC) in the Brain (2024 Review)

Transcranial Magnetic Stimulation (TMS) has emerged as a beacon of hope in the realm of psychiatry, offering a non-invasive alternative for treating psychiatric disorders. The variability in treatment outcomes highlights the necessity for advancements in personalized approaches. A recent paper analyzed the potential of personalized TMS protocols (customized based on individual brain connectivity) may help …

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Deep Brain Stimulation (DBS) of Nucleus Accumbens (NAc) for Treatment-Resistant Depression (4 Case Reports)

Deep Brain Stimulation (DBS) for Treatment-Resistant Depression (TRD) explores the cutting-edge intersection of technology and neuroscience, offering hope to those for whom traditional treatments have failed. By targeting specific brain areas, such as the nucleus accumbens, DBS attempts to modulate the underlying neural circuits associated with depression. A recent review analyzed case reports documenting significant …

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Cognitive Function Does Not Predict Response to tDCS for Depression (2023 Trial)

Transcranial Direct Current Stimulation (tDCS) has been explored as a potential treatment for major depressive disorder (MDD), particularly for patients who have not responded to traditional treatments like selective serotonin reuptake inhibitors (SSRIs). This non-invasive technique involves applying a weak electrical current to the prefrontal cortex of the brain, aiming to modulate neurocognitive functions. However, …

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tDCS for Fibromyalgia: Efficacy of Transcranial Direct Current Stimulation (2024 Review)

A recent systematic review and meta-analysis aimed to update the understanding of the efficacy and safety of transcranial direct current stimulation (tDCS) for treating fibromyalgia (FM), focusing on its effects on analgesia, antidepressant outcomes, and the reduction of FM’s impact. Highlights: Efficacy of tDCS: The analysis revealed that tDCS is effective in reducing pain intensity, …

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Repetitive TMS for Alzheimer’s Disease Alters Brain Waves & Enhances Cognition (2024 Study)

Repetitive transcranial magnetic stimulation (rTMS) is making waves in the field of Alzheimer’s disease (AD) research, offering a glimmer of hope for enhancing cognitive functions in patients. By targeting specific brain regions, rTMS has shown promising results in modulating neural activity and improving cognitive scores. This innovative therapy, coupled with real-time monitoring through electroencephalography (EEG), …

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tDCS for Insomnia & Sleep Disturbances: Targeting the Infralimbic Cortex to Ventrolateral Preoptic Area Pathway (2024 Study)

In the quest to effectively treat insomnia, a condition plaguing millions worldwide, scientists are exploring innovative treatments beyond traditional medication. Transcranial Direct Current Stimulation (tDCS) emerges as a promising intervention, offering a non-invasive method to modulate brain activity and enhance sleep quality. A recent study suggests tDCS may treat stress-related sleep disturbances and highlights the …

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