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Valerian Root for Insomnia & Sleep: Is It Actually Effective? (2023 Review)

Valerian, a herb long cherished for its sedative properties, stands at the crossroads of traditional medicine and modern scientific inquiry. Despite its widespread use across cultures for promoting sleep and alleviating insomnia, the scientific community remains divided over its efficacy. Highlights: Historical Significance: Valerian has been used since the times of ancient Greece and Rome …

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Berberine for Depression: Mechanisms & Antidepressant Effects (2024 Review)

Depression, a pervasive global health issue, significantly impairs quality of life and burdens the healthcare system. Despite the availability of numerous antidepressants, their effectiveness is often limited, pushing researchers to explore alternative treatments. Berberine, a natural compound with a diverse pharmacological profile, has shown promising antidepressant effects, offering a potential complementary or alternative approach to …

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Lactofem Probiotic as Adjunct to SSRI Antidepressants May Enhance Mood & Sexual Satisfaction in Women (2024 Study)

The link between mental health and sexual function is complex and multifaceted, with depressive disorders particularly affecting individuals’ sexual satisfaction and functionality. Recent research has highlighted the potential benefits of probiotics in mitigating these impacts, especially among women undergoing treatment with Selective Serotonin Reuptake Inhibitors (SSRIs). A new study conducted in Iran provides promising evidence …

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Antidepressants & Iron Pathways: Targeting Ferroptosis to Treat Depression (2023 Review)

Depression, a debilitating mental disorder, stands as a significant challenge to global health, potentially becoming the leading cause of disability worldwide. Recent research has unearthed a promising connection between ferroptosis, a newly discovered form of cell death, and the onset of depression, offering fresh avenues for developing innovative antidepressant therapies. Traditional Chinese Medicine (TCM) and …

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Short-Chain Fatty Acids (SCFAs) for Inflammatory Bowel Disease (IBD) (2024 Review)

Inflammatory Bowel Disease (IBD) represents a group of intestinal disorders that cause prolonged inflammation of the digestive tract, primarily including Crohn’s disease and ulcerative colitis. Recent research has highlighted the vital role of short-chain fatty acids (SCFAs) in mitigating IBD by maintaining intestinal health, regulating immune responses, and supporting the gut microbiome. Traditional Chinese Medicine …

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Berberine for Alzheimer’s Disease Treatment: Mechanisms & Efficacy (2023 Review)

In the quest for more effective treatments for Alzheimer’s Disease (AD), berberine, a bioactive compound derived from traditional Chinese medicine, has emerged as a promising candidate. Recent preclinical studies have showcased its potential to combat the debilitating effects of AD, with evidence pointing towards its ability to improve cognitive functions, reduce hallmark AD pathologies such …

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Cannabidiol (CBD): Neuropsychiatric Uses, Mechanisms, Effects on Brain (2023 Review)

Cannabidiol (CBD), a compound found in Cannabis sativa, has emerged as a substance of interest in the medical community due to its potential therapeutic benefits for various neurological and mental disorders. This comprehensive review examines the current scientific understanding of CBD’s effects on brain function, its potential as a therapeutic agent, and the ethical and …

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