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Abnormal Glutamate Biomarkers in ADHD: CDK5, MAP2, GKAP, PSD95 (2023 Study)

Attention-Deficit Hyperactivity Disorder (ADHD) is a complex neurodevelopmental condition that has puzzled researchers and clinicians for decades. Recent studies have begun to unravel the intricate relationship between ADHD and the glutamatergic system, a major neurotransmitter pathway in the brain. A newer study evaluated the roles of cyclin-dependent kinase 5 (CDK5), microtubule-associated protein-2 (MAP2), guanylate kinase-associated …

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ADHD Genetics Linked to Autism & Schizophrenia But Not Other Psychiatric Conditions (2024 Study)

Attention Deficit Hyperactivity Disorder (ADHD) is a complex neurodevelopmental condition that significantly impacts individuals’ lives. Recent advancements in genetic research, particularly Mendelian Randomization (MR) studies, have begun to unravel the intricate genetic associations between ADHD and other psychiatric disorders, offering new insights into their comorbidities. By leveraging data from genome-wide association studies (GWAS), this research …

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Genetics & Early Language Development: Vocabulary, Literacy, Cognition, ADHD (2023 Study)

Recent advancements in genetics have illuminated the complex interplay between genetic factors and early vocabulary development in children. A comprehensive meta-genome-wide association study (meta-GWAS) delves into how genetic variations influence the acquisition of vocabulary in infancy and toddlerhood. This research not only enhances our understanding of language development but also sheds light on its genetic …

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Ketogenic Diet for ADHD Treatment via Gut Microbiome Modulation (2023 Study)

Attention deficit hyperactivity disorder (ADHD) is a behavioral disorder commonly found in children, characterized by symptoms such as inattention, hyperactivity, and impulsivity. Recent research has revealed a connection between gut microbiota and neuropsychiatric disorders like ADHD. A new study suggests that the ketogenic diet could provide therapeutic benefit in ADHD by modulating gut bacteria and …

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MicroRNAs as Blood-Based Biomarkers for Early ADHD Diagnosis in Children

Attention-deficit/hyperactivity disorder (ADHD) is a common childhood-onset neurodevelopmental disorder characterized by developmentally inappropriate levels of inattention, hyperactivity, and impulsivity. While highly heritable, the heterogeneity of clinical presentation suggests complex interactions between genetic and environmental risk factors. A new study suggests that it may be possible to diagnose ADHD or detect ADHD susceptibility risk in children …

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Solriamfetol for ADHD in Adults: A New Alternative Treatment?

Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder characterized by problems with inattention, hyperactivity, and impulsivity. While ADHD has historically been considered a disorder of childhood, it is now known that symptoms frequently persist into adulthood. A new pilot study published in the Journal of Clinical Psychiatry provides the first data indicating that a newer …

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How Long Does It Take For Adderall to “Kick In”?

Adderall is a psychostimulant medication [of the phenethylamine classification] comprised of multiple amphetamine isomers: dextroamphetamine (~75%) and levoamphetamine (~25%).  In medical settings, Adderall is frequently prescribed for the management of ADHD (attention-deficit/hyperactivity disorder) and narcolepsy.  Less commonly, Adderall is utilized off-label as an adjunct in the management of refractory neuropsychiatric disorders such as: chronic fatigue …

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