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Zubsolv Withdrawal Symptoms: List of Possibilities

Zubsolv is a drug formulated with both buprenorphine and naloxone. It is primarily used to treat opioid dependency and addiction, but is also sometimes used for moderate chronic pain management. Most users of Zubsolv are taking it for opioid replacement therapy in attempt to transition off of a more potent opioid. Zubsolv is considered helpful for these individuals in that contains a “partial opioid agonist” (buprenorphine) and “pure opioid antagonist” (naloxone).

These contents give the user some degree of opioid stimulation to mitigate a full-blown opiate withdrawal, but not enough to get the user “high” – making it an ideal replacement drug. Generally when beginning Zubsolv, the goal is to stabilize on the drug, and then gradually reduce the dosage and become opioid-free. The problem is that many people neglect making an effort to reduce the dosage because they actually get addicted to it as an opioid-replacement drug.

When attempting to finally withdraw from Zubsolv, many people realize that it’s much tougher than initially expected. Although Zubsolv is certainly less potent than opioids like heroin and morphine, discontinuation (especially after long-term usage) will still pack a debilitating punch. Many people have come to realize that withdrawal from Zubsolv is so difficult, that they don’t know how to cope.

Factors that influence Zubsolv withdrawal include

If you’re withdrawing from Zubsolv, it is important to be aware of certain factors that will influence your withdrawal. These factors include things like: the time span you’ve been taking it, your current dosage, how quickly you discontinued, as well as your individual physiology.

1. Time Span

In general, the longer you’ve used Zubsolv, the more difficult it will be to discontinue. While you may not have increased the dosage over the long-term due to the fact that there’s a “ceiling effect” (in regards to dosage), your nervous system may be habituated to receive Zubsolv each day. The longer you continue any habit, whether it’s taking this drug or impulse buying junk food each time you’re at the store, the tougher it will be to stop.

Not only does your brain come to expect to receive Zubsolv on a daily basis, but your physiology expects the same production of opioids or pain-relief. Long-term users actually become dependent on the Zubsolv, making it tougher to quit. If you only used the Zubsolv for a short-term (e.g. months), it will likely be easier than someone who’s used it for years.

2. Dosage

Zubsolv comes in different dosing formulations of buprenorphine to naloxone ratios. The standard Zubsolv sublingual tablets are dosed as 5.7 mg (buprenorphine) with 1.4 mg (naloxone). It is thought that a doctor may adjust doses by increments of 1.4 mg (for the buprenorphine) and 0.36 mg of the naloxone. Eventually a patient will stabilize on a certain dose with adjustments from the doctor.

Just know that the higher the dosage you’ve taken, the more your body has come to expect the effects of the drug. Although there certainly is a built-in mechanism of a “ceiling effect” to prevent people from abusing the drug and/or overdose, this doesn’t mean that a higher dose is equally as easy as a lower one for withdrawal. Generally the more you increase, the tougher it is when you decrease and/or discontinue.

3. Cold Turkey vs. Tapering

Some have argued that it makes no difference whether you quit cold turkey or taper. While cold turkey may sound like an appealing idea, if you couldn’t handle the effects of discontinuing an opioid and needed to take Zubsolv in the first place, you may want to consider tapering. Feeling good on Zubsolv can make it seem like quitting cold turkey will be easy, when in actuality it shocks the entire nervous system.

Cold turkey is associated with more severe earlier stages of withdrawals and greater likelihood of protracted symptoms due to the fact that the nervous system may go into shock. By conducting a gradual taper prior to completely discontinuing, you’re allowing your body and brain to adjust to the slow changes in dose. This theoretically should make withdrawal symptoms much easier than discontinuing from a high dose. The slower the taper, the less severe the withdrawal symptoms should be.

4. Individual

No two people are identical when completing a withdrawal. Withdrawal for one person may take 2 months and for another may take 4 months before they feel noticeably better. Avoid comparing your withdrawal duration and symptoms to other people. While you may share some commonalities with another person, the length and severity of your withdrawal will likely be subject to individual variation.

It is important to consider things like: your individual physiology, whether you take other drugs or drink alcohol, your genetics, social support, and lifestyle when thinking about withdrawal. One person may have extremely low stress, great social support, be drug and alcohol free, and stay busy during withdrawal to help take their mind off of symptoms. Another person may have a lot of free time, be a smoker, and have high stress – which could compound the withdrawal.

Zubsolv Withdrawal Symptoms: List of Possibilities

Below is a list of symptoms that you may experience when discontinuing Zubsolv. Keep in mind that you may not experience every single symptom on the list. This is a collective list of symptoms people have reported when they’ve discontinued.

  • Agitation: Many people feel extremely agitated when they quit Zubsolv. The agitation may result in you to pace back and forth or move around excessively. You may feel as if you cannot sit still because internally you are wired with nervousness and discomfort.
  • Anger: While the first few days of withdrawal may result in a person feeling extremely tired and debilitated with fatigue, a person may start to get some energy back. When a little energy returns, they may not like how they feel and every little thing may make them angry. If you notice you’re feeling intense anger, realize it’s normal. Try to channel it productively rather than using it as an excuse to lash out on others.
  • Anxiety: The Zubsolv may actually have helped with anxiety while taking it. When you discontinue, your brain is no longer getting the partial-opioid stimulation from the Zubsolv, and you feel depressed. It may take awhile for your anxiety to lessen due to the fact that your brain will need to elevate its endogenous opioid levels, which will take time.
  • Body aches: Your body may become extremely achy and you may develop cramps when you withdraw. Realize that these aches are likely a result of abnormal endogenous endorphin production. Your endorphin levels are likely low due to using Zubsolv for an extended period, which leads to aches. As they return to a baseline, the aches should improve.
  • Brain fog: It is very common for people to experience brain fog riddled with concentration problems and memory issues. This is largely due to the fact that in the early stages of withdrawal, you are hit hard with an array of physical and psychological symptoms. It becomes nearly impossible for you to think about anything other than the unpleasant symptoms.
  • Cravings: Perhaps one of the most troubling symptoms to experience is that of cravings for Zubsolv or other opioids. It may be tempting to take another Zubsolv and your animal brain is probably trying to entice you to avoid the current pain that you’re enduring and get back the “pleasure feeling.” Realize that these cravings are likely going to be more intense during early stages of withdrawal. Each consecutive day you go without opioids, the easier withdrawal becomes.
  • Depression: Your brain is no longer getting the opioid stimulation that it had gotten from the Zubsolv. When you withdraw, your opioid production may be lower than average. Neural activity as well as neurotransmitter levels will be temporarily out of balance, especially in the early stages of withdrawal. The combination of lack of opioids and neurotransmitter level imbalances can lead to severe depression.
  • Depersonalization: You may feel as if you aren’t your true “authentic” self anymore. It may seem like an alien has hijacked your body and you are still living in it, but you just feel “weird.” Depersonalization is common when going through any drug withdrawal and means that your brain and physiology is nowhere close to being fully healed. Accept that you don’t feel like yourself, and know that you eventually will.
  • Diarrhea: Some people experience intense diarrhea when they initially discontinue any opioid drug. This is because when taking an opioid, it is common for people to become constipated. When the effects of the drug leave the system, you may find yourself on the toilet more than usual.
  • Dizziness: Feeling dizzy is something that nearly every person will experience when quitting Zubsolv. The dizziness may be mild, moderate, or severe depending on how quickly you discontinued. It may feel as if the room is spinning in the early stages of withdrawal, but it’ll eventually improve.
  • Fatigue: It is common to feel extremely fatigued when you quit Zubsolv. This may be among the most debilitating withdrawal symptoms of all. You try to get some work done around the house, but you can’t because you’re too tired. Even simple tasks may make you feel totally exhausted. While it is important to take extra time to “rest” so that your body recovers, don’t overdo the resting. Sometimes it’s necessary to push through the fatigue a little bit and dig deep to get something done.
  • Headaches: Another symptom that nearly everyone experiences is that of headaches. It is important to stay hydrated and consider taking supplements to help reduce the intensity of strong headaches. Get plenty of rest and accept that headaches are an inevitable part of the process.
  • Heart rate changes: You may notice that your heart rate changes significantly compared to when you were taking Zubsolv. This is a common reaction that people experience as a result of physical dependence. Engage in some sort of relaxation exercise to help lower your heart rate if it shot up.
  • Insomnia: The first few weeks of withdrawal may be characterized by sleepiness, but eventually you may transition to a point of intense agitation, anxiety, and insomnia. If you find that you cannot fall asleep, you may want to consider supplementing melatonin and/or engaging in some sort of relaxation exercise like mediation.
  • Irritability: Most people feel extremely irritable for awhile after they’ve quit Zubsolv. Even though it may seem like you’re doomed to an eternity of irritability, you can reduce the irritability by engaging in a relaxing or soothing activity when it strikes.
  • Joint pain: In addition to body aches, you may specifically notice that your joints are in pain or throbbing. The joint pain may be a physical reaction that your body is having in attempt to function without the drug. It had come to rely on the subtle opioid properties for pain relief, but it’s no longer getting them.
  • Mood swings: Don’t be surprised if your mood is all over the map during withdrawal. One day you may feel exhausted, another day mad at the world, and another day hopeful for the future. Realize that your mood will fluctuate as your nervous system and brain recalibrate themselves to homeostatic functioning.
  • Nausea: You may become nauseated to the point that you feel like throwing up. Nausea is most likely to occur in the earlier stages of withdrawal, and should lessen after a few weeks.
  • Palpitations: It may feel as if your heart is pounding loudly or uncomfortably fluttering in your chest. These are a common physical reaction associated with drug withdrawal and increased anxiety. Do your best to accept them as a withdrawal symptom and realize that they’re not the same thing as a heart problem; these are medically benign.
  • Restlessness: Many people complain of restlessness and restless leg syndrome during discontinuation. This involves feeling an uncomfortable sensation of creeping, throbbing, pulling, or energy in the legs that provokes movement. This is an inevitable symptom of withdrawal for many and can be very annoying, but will subside over time.
  • Sleep problems: At some stages of withdrawal you may end up sleeping excessively, while during other stages you may end up not getting enough sleep. Sometimes you may sleep for awhile, but wake up feeling like you hadn’t slept at all. Do your best to fight through the sleep issues and realize that your circadian rhythm will eventually reset itself.
  • Sweating: A very common symptom associated with Zubsolv withdrawal is that of sweats. You may find that you perspire in excess throughout the night or all day. Some people sweat around the clock as a result of the body detoxifying itself and attempting to function without the opioid.
  • Swelling: Some people may notice that their limbs (e.g. arms, legs, etc.) swell up. If you notice that your limbs have become swollen, it’s directly related to withdrawal. Know that in a few days the swelling should gradually begin to subside. It may be alarming to swell up during withdrawal, but it’s a reaction that some people have upon discontinuation.
  • Vomiting: Many people feel extremely sick when they stop the drug. This is due to the fact that the body developed a tolerance to its effect and is now in a state of backlash. The combination of many symptoms such as nausea and dizziness can easily provoke vomiting. To reduce the chances of vomiting, make sure to slowly taper.

Note: If you have experienced a symptom that isn’t on this list, feel free to mention it in the comments section below. Also consider reading about Suboxone withdrawal – a relatively similar drug to Zubsolv.

How long does Zubsolv withdrawal last?

There is no definitive timeline that can be stated for Zubsolv withdrawal. In general, most people find that the first couple weeks have the most severe symptoms. After several weeks, things may seem to slightly improve. After a full month, many people finally start seeing some positive signs of improvement. Realize that the length of your withdrawal is highly individual, therefore asking how long it will last is futile.

It is important to keep in mind that it will eventually end, and therefore your focus should be on improving as quickly as possible. To maximize your chances of a quick recovery, you’ll want to make sure you are eating a healthy diet, socializing, staying as busy/productive as possible, getting some light exercise, and not dwelling on your symptoms. I recommend giving it a full 90 days before you reevaluate your symptoms.

This isn’t to say you’ll be 100% better in 90 days, but it’s just to motivate you to get to the 3 month marker after full discontinuation. At this point you’ll realize that the worst stage of many symptoms is completely over. If you’ve been on Zubsolv and are currently going through withdrawal and/or have already made it through withdrawal, feel free to share your experience in the comments section below.

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{ 41 comments… add one }
  • Amanda April 17, 2015, 1:04 am

    Hi I’m on day 5 of withdrawal from taking Zubsolv and tapered down to a very very small amount before quitting cold turkey. Most of my symptoms have been lots of hot and cold flashes, chills, and super sweats. Seems to be much better today but still there – more sweating today than chills and flashes, last night was my worst night with restless legs and sleepiness. Mood swings are there too, but I’m staying hopeful and looking forward to the new normal for me! I keep my mind busy and stay doing something to keep me busy as well. I can only hope it will all get better in the next few days to come.

    • Andrea April 1, 2016, 6:33 pm

      How long and how much zubsolv were you on? I am starting to wean myself off. Any advice you can give me would be great. I was on 5.7 mgs 3x a day. Trying to go down to 2 or 1 a day.

  • Julia May 6, 2015, 6:15 pm

    I would like to add a few more on the list of things that you may experience. Not wanting to eat, the feeling you need to keep swallowing, your senses are heightened from sensitivity to touch, sound, and you will experience certain smells. For me it was the smell of Garlic that went on for about five days. Today is day 8 for me and I am feeling better, but still sweating. Good luck to anyone who is trying to quit, don’t give up.

  • brad May 20, 2015, 1:43 am

    It has been about 2 weeks off zubsolv. Was on it or suboxone for about 3 years after 10 year pill addiction. The first 2 days weren’t bad, I felt fine. The 3rd-7th day were bad, but not opiate bad. Just no sleep, aches and pains, and cravings were bad. I got multivitamins and some advil and melatonin. I am already feeling better, mornings are still rough, but getting better. If possible I would take at least a week off work. Diarrhea is still really bad.

  • Ann Cheney July 8, 2015, 6:22 am

    Weaning off Zubsolv was not particularly easy for me. I tried to taper my dose very gradually (though I was not given a tapering dose by my doctor who had prescribed the Zubsolv several years ago for my Fibromyalgia.) When I went into acute narcotic withdrawal, I had my husband take me to an ER. I was given IV fluids, IV Phenergan (for nausea) and IV Toradol (a NSAID) plus when I was getting ready to be discharged after 7 hours in the ER, I was given oral prescriptions to fill.

    They were: Hydroxyzine (generic Atarax) for restlessness, generic Zofran for nausea and Dicyclomine for abdominal cramping or muscle spasms. I thought the nausea, agitation, anger, muscle pain in large muscles of my back and thighs, insomnia, weakness and fatigue were my most difficult symptoms. I am 18 days out from when I went to the ER my first time and I am now able to eat more as my nausea is less and my muscle pain and irritability and anger has subsided some. I still have some withdrawal symptoms but I can tell I am improving some.

    I did have to go to the ER a second time about a week out from the first time due to extreme weakness related to continued nausea. I was given another bag of IV fluids, one dose of IV Phenergan and one dose of IV Toradol which helped. I think the amount of anger I had completely took me by surprise but I don’t have that amount of anger now. I a glad to be off the Zubsolv. I hope this information from my withdrawal experience is helpful to someone. Bless you.

  • lisa August 21, 2015, 1:45 am

    I have been on zubsolv for 2 years now after taking Suboxone for 2 years. I know it’s time for me to to start resuming and eventually come off but I am really scared. I have a 10 year old daughter and I need to be 100% focused for my high pressure job. Not sure if the above weaned themselves off or went cold turkey. Can someone explain to me if there’s a difference?

    • Layrence August 25, 2015, 3:49 pm

      Hi, I am day 23 on Zubslov w.d. I also have a high pressure job (attorney). I will not lie, it was a terrible experience. The worst was the loss of sleep for so long. Fortunately, I picked a slow time at work when a lot of people we on vacation. I was not very productive for about a week, but I could function. Try to take your last dose (wean down as much as you can) on a Thurs., so the worst symptoms will hit on the weekend. Maybe take a day or 2 off work (easier said).

      Here is the good news, there is an end point. I do not feel the intense symptoms any more. A lot of lethargy and some depression, but those will eventually pass. You can do this…try to get a Dr to give a script for something to help you sleep. That saved me. Good Luck!!

  • Heather October 17, 2015, 12:50 am

    BE WARNED I was told people could take this for years and it was OK. I started a seven year addiction to Percocet due to a bad car accident. I overdosed this year of 2015. Went to rehab and they gave me suboxone. Unfortunately when I left my insurance didn’t approve it so zubsolv it was. I’m six months sober. about a month ago I told my doctor I wanted to taper off. He properly tapered me off zubsolv. I am on day four and still feel like hell.

    Day 2 was the worse I heard voices, cold, sweats, weak, depressed, cant leave the house, feel like I’m about to die, heart palpitations, cant eat and diarrhea. I’m extremely dehydrated and my husbands trying to get fluids in me that don’t wanna go in and stay in. My current doctor said I’m suffering with acute withdrawal syndrome to zubsolv. the only solutions are comfort meds and the symptoms can last to 1-3 weeks. Plus there is a post acute syndrome that last 2 years. Zubsolv IS DANGEROUS.

  • Miguel November 8, 2015, 9:03 pm

    I’m on zubsolv for 2.5 years and I’m tapering off. I’m cutting the 5.7 mg in 4 pieces and I’m taking 1 piece a day. I’m already feeling WD symptoms. Can someone that did this email me and tell me their experience please?

  • Mary November 24, 2015, 11:00 pm

    Hi, I was addicted to opiates since I was 16 due to a prescription for my chronic back pain and surgery. I would be dead if it weren’t for my doctor, suboxone/zubsolv, my family and my boyfriend. I know that all for a fact. It has now been over 5 yrs on zubsolv, I tapered from 3 to 2 per day. And now I have to wait over a month for insurance from my new job. I’ve broken up my last few pills to help ease into WD, but I’m basically going cold. Anyone else experience this? Any tips for me heading into no medicine days? Any would be helpful!

  • John November 29, 2015, 7:32 pm

    I have been off of zubzolv for two weeks and it’s been extremely horrible. I used the taper method and the last week I was on them I was taking a half every other day. Since I have stopped cold turkey I haven’t slept hardly at all and I don’t eat because of the nausea and diarrhea. It’s not gotten any better in two weeks and it’s driving me nuts. I basically have to lock myself in a room and stay away from people because of the mood swings. I wouldn’t recommend anyone ever taking this medication or quitting cold turkey.

    You would be better off going to a rehab facility. I don’t know how doctors and medical companies sleep at night. They prescribe one medication that gets you hooked and replace it with another that’s just as bad. If anyone needs someone to talk to feel free to email me. Believe me I know how it is when you are going through this and nobody understands or cares what you are going through.

    • Angel December 31, 2015, 11:37 am

      Hi I’m very interested to know how the withdrawals progressed and hoping you didn’t relapse or need to replace by taking a different prescription drug? I was a heroin addict for around 2 years then on suboxone for another 2 years (but with a few relapses to H if I ran out of meds). I then got out onto zubsolv and realized it’s just as hard as suboxone to manage without.

      So because I couldn’t afford a rehab, or any more meds, I tapered myself off by breaking the last pill into minute crumbs. Now it’s been 7 days without anything and the withdrawals have been nasty needed Imodium and have been drinking alcohol (but not excessively )to try and help me fall asleep.feel very angry emotional and sometimes awful anxiety attacks but if I stay occupied or force myself to go outside it helps.

      I’m lucky not to have a job at the moment or should I say I’ve chosen not to work as I can’t function during this. I’m on a very tight budget and need to work again ASAP. I just wonder after week 1 how long it will last??? I’m determined not to relapse to heroin and thank God I’m not actually craving it at the moment. Best of luck to anyone going through this hell!!!

    • MICHELLE May 3, 2016, 4:13 pm

      I was on norco 10/325 for 7 years fro my DJD in my back, I work 12 hour shifts and I am on my feet a lot. I was prescribed Zubsolv 07/2015. I am now trying to taper off. Reading everyone’s experience coming off zubsolv really scares me. I am moving to another state and starting a new job. Should I take a couple weeks off to get my head right before I start my new job? I have started trying to exercise, anything to feel normal. I would appreciate any suggestions.

    • Ellie steinbaugh May 24, 2016, 11:53 pm

      Have been on zubsolv for 9 months but really want to get off of it. I am frightened of all the horrible things I have heard about any type of way to get this stuff outta my life. Go to a clinic everyday, they just want to keep you coming back, they make you feel real bad when you suggest a tapering concept. I believe it’s a racket all about the money, but I’m concerned about just stopping on my own, don’t know what to do!!!!!

    • Nate September 6, 2016, 1:49 pm

      I don’t know how they sleep either. My doctor was hanging my dependency on zubsolv and indirectly her over my head by making up unnecessary appointments, (not cheap as she didn’t go through insurance) and saying if I didn’t go to the appointment then she would cut me off the zubsolv. I cut her out of my life and unfortunately am going cold turkey. I don’t know how she lives with herself. Worst drug dealer (which is exactly what she is) I have ever had by far.

    • DAKOTA October 4, 2016, 5:49 pm

      I am weaning down from 2 & 1/2 a day and I am down to 1 & 3/4 a day and it is very hard for me. I haven’t been to work in 2 days and there is no way for my boss to really understand what I am going through as he has never been an addict. I have been on ZUBSOLV for a little over a year. The last two days when I have been woken up by my alarm to get ready for work I have just woken up irritable – extremely irritable to the point that I want to sock anyone that comes near.

      I have dealt with horrible sweating the entire time that I have been on this medication and my doctor basically says there is nothing we can do about it except getting me stabilized. I think if I had ever been truly stabilized the sweating would have stopped eventually but it hasn’t. I have worn my sweater the entire time through the hot mid-west summer.

      I have had horrible restless leg problems the last two mornings as well. I don’t know how to make this stop but it has to because if it doesn’t then I am afraid of losing my job which is also high pressure everyday all day.it seems as though I never get anytime to relax and let my body and mind relax because if they aren’t complaining cause I didn’t come to work they are complaining that I didn’t come to work it seems like all they care about is the production at work not if the employees doing the production are happy and healthy.

      Working a full time job plus having a 3 year old to care for and school things to do plus taking this med and dealing with the stress of that is getting to me and I don’t know what to do. I need time to let myself truly relax but I’m not allowed to per my job and my busy life, so I need some help or ideas or something please and thank you.

  • Jenny December 13, 2015, 2:00 am

    Don’t forget about the watering eyes and the urge to yawn all the time coming off this devilish medicine.

    • JD July 29, 2016, 4:19 pm

      That and I am constantly sneezing. I tapered for 8 months down to the lowest dose they make and I would cut the pill into 1/4 and take a quarter a day. I believe it was the 1.4. I am feeling alright for the most part as I am on day 5 of nothing. Yawning sneezing and watery eyes. Can’t forget the hot/cold sweats.

  • Katie December 13, 2015, 3:03 pm

    I’ve been addicted to pain medication since I was 16 years old following a car accident that left me with several back injuries and a titanium femur. I have been prescribed zubsolv as an alternative to opioids and I am looking to wean down to minimize withdrawal symptoms. I went 1 week cold turkey and the symptoms were unbearable. I gave in and filled the new script that was given, however I am looking for the best way to taper so that the withdrawals are minimal. Any advice would be appreciated.

  • Andrea Brackin December 27, 2015, 1:46 am

    I been on zubzolv 3 months but I only take a tiny chunk twice a day. It doesn’t last a full 24 hours. If I don’t take a piece after about 14 hours I am sick to my stomach and I get the horrible sweats. Does this seem right or could it be something else making me this way? Usually if I take a piece before bed I am OK, but if I wait until the next day, I am sick by the time I wake up.

    • james February 3, 2016, 11:49 pm

      I had the same experience. Usually symptoms returned after 14-18 or so hours.

  • Mary January 9, 2016, 1:53 pm

    It has been almost six weeks since I went cold turkey and I’m finally becoming a real person again. Anyone who is in their first few weeks, yes it seems unbearable. I experienced every symptom I have ever seen and I continued to push because it just started to piss me off that I wasted so much time already.

    I’m still getting better everyday, but it really took off once I got through those really anxiously shaking days. I am telling you, you can do this. Just remember your body is going through this to rid itself of this medicine that is plaguing your body. Please don’t give up!

    • Steve February 24, 2016, 8:28 pm

      Of all the posts I read here on my 7th day of withdrawal, I have to say, yours was the most promising. Thank you for your input. Truly is hell, but in a strange sort of bearable hell…LOL. Only an addict can understand it. Peace

  • james February 3, 2016, 7:52 pm

    After a very serious 10 plus year opiate addiction (up to 20 30mgs per day for years) I decided I had to stop, I tried multiple times without success previously with some of the most awful withdrawal symptoms imaginable including receiving IV fluids after one attempt. I used zubsolv for 10 days, 2 5.7 mg once a day for 6 days, with a couple times an extra at night for first few days. After seven days I went to 1 for three days and then stopped completely.

    I have some fatigue, but I am so happy I stopped before getting addicted to Zubsolv. I feel 90% better and improving every day, of course I follow doctor’s instructions, but these long term Zubsolv scripts may be helping the pharma companies more than anyone else. I have a high stress finance job and work 10-12 hours a day.

    I can’t tell you how much better things are now. Hope this helps someone. Trading one addiction for another is not doing much good in my book.

  • gina March 13, 2016, 5:31 am

    My sister has been on zub for just over2 years but she doesn’t take a full pill a day, it’s been just over a quarter for about six-months. I know she is scared to quit and doesn’t know if she can get any time off work, but we have been talking and she is ready to seriously get her life back. I know I can’t help the irritability and anger she’ll be feeling, but is there anything I should have on hand besides maybe some Gatorade?

    What about sleep pills for the insomnia, would that help or hurt? She won’t get a docs help with this, but I was wondering if there is anything over-the-counter or supplements that could help her through the worst of it?? Any advice would be greatly appreciated. :)

    • Dawn March 17, 2016, 12:00 pm

      I tried tapering off last fall with no success. I need to get off Zubsolv but am so fearful of the withdrawals! I have a dr’s appointment tomorrow to see what steps are necessary!

      • nlee April 9, 2016, 10:47 pm

        I’ve tried and tried and tried and finally I have succeeded so please keep trying. Your brain will eventually get the drift & you will just do it. =)

  • Lisa April 7, 2016, 2:00 pm

    Has anyone had severe rhinitis (sneezing, itchy,watery eyes, etc.) during withdrawal from zubsolv? I was on Suboxone for about 3 years and switched to Zubsolv for about 3 years as well. It’s been a little over 2 months since I’ve been completely clean and I feel much better mentally and physically, but the severe rhinitis I’ve been experiencing is so frustrating…

    • Steve May 8, 2016, 12:53 pm

      Lisa, I sneeze all the time also! A “Normal” (lol) withdrawal symptom apparently!! I’m six weeks off!

  • nlee April 9, 2016, 10:45 pm

    Today is Saturday April 9th 2016 & I can say I am on day 4 of no zubsolv. First night was really bad. Fever, can’t sleep, toothache, (Something that’s been there but masked BC of the meds). Every time I lay down my stomach goes in knots. I can’t stop sweating & the chill bumps never end!! I know this wont last forever – I can already tell that my body & my brain are coming back to life.

  • Steve May 8, 2016, 1:00 am

    I’ve just completed week six from zubsolv use! Yeah, It’s still a bugger. Sleep is coming back slowly… I started at 16/4 mg./day and had worked my way down to 1.4/.36 once daily over 3 years of use. I knew it was going to be a son of a gun and it didn’t disappoint! Like the withdrawal symptoms above said fatigue is the worst.

    I stand 8 hours a day at work. I still have to sit down from time to time as I get exhausted easily. Some days are better than others. DON’T QUIT or GIVE IN!! It does get better! And I am also a recovering alcoholic / addict 3+ years sober (minus the zubsolv). You can do it if I can LOL! What a wicked drug!!! Only Advil and tylenol for me for my pain… Good luck to all!!

  • mark May 26, 2016, 12:34 pm

    Day 11 of Zubsolv withdrawal. Was on Suboxone or it for 5-6 years. Tapered down to two a week then ran out. Feel horrid. I thought the liquid bowl movements and gas were bad…then nausea hit at 3:30am today. Haven’t been to work all week. Guess whose rent will be waaay late. No appetite. This sucks.

  • Gail June 25, 2016, 1:16 pm

    What a horrifying list of symptoms! I’ve been taking Subutex, then switched to Zubsolv for years for fibromyalgia. As I’ve been tapering off of Zub, I was also tapering off of Trazodone for sleep. I’m happy to say my w/d symptoms are minimal compared to what others are experiencing: sleep disturbance, fatigue, pressure in my chest.

    Most days I now take no Zub, but occasionally will take 1/4 or 1/2 – if I do this before 1 pm, I will sleep through the night. Yesterday, I took 1/4 at about 1:30pm & felt so energetic & great even into the evening, that I thought my symptoms were over–until I had a sleepless nite! Anyway, I count myself lucky after reading everything here–perhaps others of you will as well. Good luck!

  • Donna June 27, 2016, 6:53 am

    I have been on suboxone or zubsolv for 3-4 years, buying them off the street the first 2 and a half years while also taking hydrocodone. Whichever I could find to not withdraw. Was addicted to hydrocodone for 6 years. I got pregnant last year, April 2015, and finally went to a doctor to get suboxone prescribed. If you withdraw while pregnant, it can harm or kill your baby. So I sought out help.

    What makes me a true addict I would say… When I was not going to a doctor, I was making one suboxone strip last me nearly a week if I couldn’t get pills. Then sought help from a doctor and thought that I would finally end my addiction. But instead the doctor prescribed me TWO a DAY. I should of said no, if I even could of, but I am an addict. My doctor could care less.

    While pregnant and working on my feet long hours, I increased to 1 a day then eventually to 2 a day. Not what I thought would happen. I planned on stopping, especially since I was pregnant. But you are replacing one addiction with another. And so I abuse it some days and others I only take one not two. It’s a battle to stop and it is just as bad as the opiate’s.

    If you are seeking help and want to get on zubsolv, research and do what you have to do to stop as fast as possible. Because before you know it, it will be a year and a half or 6 years later. And you will feel like there is no end. This stuff can and will be addicting if you let it. So do not go to a doctor that doesn’t care.

    I literally never see him, only the nurses, and have to pay so much money and the prescription is just as expensive (no insurance). I want off so bad and have not been able to do so. It’s frustrating and expensive. I want to stop, have to stop, and will try the taper method. Reading what everyone has wrote has helped me make my mind up. I’m letting the drug win and hope I can come back here one day and tell you I have stopped completely and give you better advice.

    Reading what others have written makes me feel not so lonely in this battle. Not the only one struggling. I commend you all who have stopped or in the withdrawal stages. Being an addict is the worst thing I’ve ever done to myself. And I’m truly tired of the struggle!

    • Kellie August 26, 2016, 8:40 pm

      Prayers Donna.

  • Kellie August 26, 2016, 8:37 pm

    Hello. I began taking Suboxone two years ago for Fibromyalgia. After my new insurance refusing to cover it I switched to Zubsolv and was on it for almost a year. I felt like this medication was not helping with this type of pain and decided to stop because of the way it affected my ability to think and work. My intentions were to taper, but after my last visit with the pain DR.

    I got so frustrated that I never got the medication filled. I just wanted it out. I was so fearful of the withdrawal, but for me, and I understand everyone’s body is different, the withdrawal was mild and smooth. Minor sweating, and minor frontal lobe headache. I kept busy, kept going to work, and did not stop my daily routines.

    I was taking three of the 1.4s a day for pain. I am so thankful to be off of this drug. I read the craziest things online, people using this drug in the wrong ways. This drug was created for a reason and it should be taking as prescribed. Cold Turkey may not work for everyone, but it did for me. Thank You,

  • Sam September 6, 2016, 5:40 pm

    I abused opiates during my teenage years and became addicted to heroin for 9 months. I was prescribed Suboxone for a week or two and then transitioned to Zubsolv due to the side effects of Suboxone. I have been taking Zubsolv for 7 months and have been tapering from two 5.7mg tablets per day to one a day, and I have attempted to stop cold turkey after taking one every other day or so.

    I can go almost three days without taking one until experiencing almost unbearable withdrawal symptoms. The worst have been sweating, fatigue, loss of appetite, thirst, restlessness, insomnia, pain, irritability, and headaches. I try and curb the withdrawal symptoms by drinking kratom after a day or two without taking Zubsolv and that seems to help until day three.

    I have started splitting the 5.7mg tabs into two pieces and taking one every few days when I need something to counter the symptoms and I run out of kratom. It has been a few weeks of taking pieces of a tablet every 3 or 4 days, and I am still experiencing symptoms that keep me from sleeping or functioning normally. I have been absent from work for two weeks and am wondering when this will end, and if I will be able to replace the habit with kratom, which I do recommend.

    The symptoms are not as bad as the withdrawal from heroin, but I never expected to have to go through this kind of horror again.

  • Diana September 18, 2016, 8:40 pm

    I started taking opiates after several collapsed lungs. Doctors followed that with lung surgery on each side. This had left me on opiates for 4 years. After that, I was addicted and never stopped going to the doctor for more. I held a great job and did well for my family.

    Finally, one day I looked at my 9 year old daughter and realized that I had been dependent on pills for her entire life. So I went to my doctor and asked for the Suboxone which was later changed to Zubsolv. I will say that the Suboxone worked to help me realize that life without pills was a real possibility. I stayed on the Zubsolv for almost 2 years.

    But I am now on Day 9 of going cold turkey and I too have experienced every symptom here. I worked through the entire process so far. I am determined to not ever be dependent on drugs again. I am going to make it through this and you can too. Don’t give up! If I can do this so can you. Remember every day gets better!

    • Vivian December 6, 2016, 5:02 pm

      I was on Norco 10 mg for 5 years bc of an auto accident. Before that I never took a pill was in the gym everyday for 10 years, looked and felt great. After I decided to quit the pain pills bc mine would get stolen every once in a while, and I went through pure hell, I went to my Dr and they put me on Suboxone. Lost my insurance and got enough money to go to a cash only clinic and began taking Zubsolv.

      I was prescribed 3 a day, but never took over one or a half a day for 2 years. Decided to get off those bc couldn’t afford them. I’m probably considered a mild addict to some of you all. I feel so bad for you. Even though I was taking such a low dose, it’s been really miserable. I’ve had most of the symptoms you’ve described. I’m into day 5 of no meds. Restless leg has kept me up every night, sweats, chills, I also like one lady said smell garlic and sneeze a lot.

      I don’t know if it’s the sweat that smells or just a symptom. I take klonopin to help with anxiety and heart palpitations. Best thing for restless leg is a warm bath, at least it’s relief for a while. I have it so severe it goes into my arms and upper body. Oh, also lots of magnesium helps too. If my Dr, after I’d had the wreck would have told me what my life was going to be after I became addicted to the pain killers, I’d never never taken them.

      Drs are bigger drug dealers than the ones in prison and on the streets, it’s just legal, greed. Your stories of success have encouraged me. Thank you!!! I was considering getting a pain pill just to feel better for a while, but changed my mind. For no more than I took, it’s been hell for me and I don’t know if my system is just more prone to addiction or what. But you all can do it, just like I’m going to and God bless you all.

  • Kelsey September 19, 2016, 9:36 pm

    Well tonight will make 72 hours that I’ve been without zubsolv. I have been taking a half of a 5.7mg a day for about a month. This last week taking it every other day. And about three days ago I just stopped feeling like taking it. I’ve been extremely lethargic and depressed but besides that I’ve been fine. I’ve been resisting the urge to take a fourth of a 5.7 just out of boredom at this point.

    The only thing that’s really been helping is I’ve been getting pretty drunk the last few nights. That’s been helping with my mood and giving me something to look forward to all day to keep myself from taking some more. But I’m hanging in there. Really hope that it doesn’t get any worse. My little cousin said he just felt lethargic for a few days when he stopped taking subs after a months use so I’m hoping this will be it.

    I’ve withdrawn from subs after a years use of 3 strips a day cold turkey and it was miserable. Took about 4 days to start feeling bad… so hopefully this time will be different since I’ve only been on it for a month and at a much lower dose than last time. Wish me luck! And I hope this helps someone. Post again in a few days and let y’all know how it goes.

  • Eric D October 11, 2016, 6:20 pm

    Hello, cold turkey for a week and then took one. My GF and I (she is now in rehab and bout to come back) were splitting mine, so I wasn’t taking a prescribed dose. I figured when she left I took it a few more times and try to stop. It wasn’t awful, if you used pills or dope, you know awful. It’s more annoying. The worst were sweats, I sweat all the time, the sleep was either OK or bad.

    Lot of nightmares. I don’t take sleep meds, but do take neurontin and catapress at night, so that put me out for a few hours. I fought through the tiredness, seems to me I’d start the day tired but by night I was good. I’d walk to the store and back at 7 am just to feel like I can get past it. It was a 20 min walk – about 8 blocks. I have cold turkey’d off dope, Percocet, Suboxone like 3 times and methadone. I will get this done.

    I just remind myself of dropping from 80 mg of methadone to 35 mg in a couple months, then dropping out for good. I bought a few people’s take home for the times I needed to attend family functions, and of course didn’t want to look sick. But it was awful. It lasted 4 months before I’d felt like I could crawl out of the house. Luckily my GF at the time s, parents let me stay w her in a farm house 2 hrs from the city in the middle of nowhere.

    I had money but no drive to get up, dressed, trudge threw feet’s of snow…etc. just thinking of that time gives me chills. We can all do this. Get a therapist, and if you have a BF or GF, tell them you want sex whenever you can. It helps a bunch, or masturbate. Sounds funny, but it gets you light exercise and getting off releases endorphins. Drugs are a nuisance to enjoying life. To bad it took 20 years to learn.

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